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1

Classification of Cytochrome P450 Activities Using Machine Learning Methods

Hammann, Felix, Gutmann, Heike, Baumann, Ulli, Helma, Christoph, Drewe, Juergen

Journal:

Molecular Pharmaceutics

Année:

2009

Langue:

english

Fichier:

PDF, 92 KB

english, 2009

2

Comparison of the dissolution and pharmacokinetic profiles of two galenical formulations of the endothelin receptor antagonist macitentan

Oliver Kummer, Manuel Haschke, Felix Hammann, Michael Bodmer, Shirin Bruderer, Yann Regnault, Jasper Dingemanse, Stephan Krähenbühl

Journal:

European Journal of Pharmaceutical Sciences

Année:

2009

Langue:

english

Fichier:

PDF, 357 KB

english, 2009

3

A Binary Ant Colony Optimization Classifier for Molecular Activities

Hammann, Felix, Suenderhauf, Claudia, Huwyler, Jörg

Journal:

Journal of Chemical Information and Modeling

Année:

2011

Langue:

english

Fichier:

PDF, 3.10 MB

english, 2011

4

Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide in Healthy Subjects

Dolder, Patrick C., Schmid, Yasmin, Steuer, Andrea E., Kraemer, Thomas, Rentsch, Katharina M., Hammann, Felix, Liechti, Matthias E.

Journal:

Clinical Pharmacokinetics

Année:

2017

Langue:

english

Fichier:

PDF, 938 KB

english, 2017

5

An automated screening method for drugs and toxic compounds in human serum and urine using liquid chromatography–tandem mass spectrometry

Stefan Sturm, Felix Hammann, Juergen Drewe, Hans H. Maurer, André Scholer

Journal:

Journal of Chromatography B

Année:

2010

Langue:

english

Fichier:

PDF, 624 KB

english, 2010

6

Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone

Oliver Kummer, Felix Hammann, Claudine Moser, Olivier Schaller, Jürgen Drewe, Stephan Krähenbühl

Journal:

European Journal of Clinical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 196 KB

english, 2011

7

Combinatorial QSAR Modeling of Human Intestinal Absorption

Suenderhauf, Claudia, Hammann, Felix, Maunz, Andreas, Helma, Christoph, Huwyler, Jörg

Journal:

Molecular Pharmaceutics

Année:

2011

Langue:

english

Fichier:

PDF, 474 KB

english, 2011

8

Decision tree models for data mining in hit discovery

Hammann, Felix, Drewe, Juergen

Journal:

Expert Opinion on Drug Discovery

Année:

2012

Langue:

english

Fichier:

PDF, 376 KB

english, 2012

9

Computational Prediction of Blood-Brain Barrier Permeability Using Decision Tree Induction

Suenderhauf, Claudia, Hammann, Felix, Huwyler, Jörg

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 269 KB

english, 2012

10

Green tea extract enhances parieto-frontal connectivity during working memory processing

Schmidt, André, Hammann, Felix, Wölnerhanssen, Bettina, Meyer-Gerspach, Anne Christin, Drewe, Jürgen, Beglinger, Christoph, Borgwardt, Stefan

Journal:

Psychopharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2014

11

Breast Cancer Resistance Protein and P-Glycoprotein Expression in Patients with Newly Diagnosed and Therapy-Refractory Ulcerative Colitis Compared with Healthy Controls

Gutmann, Heike, Hruz, Petr, Zimmermann, Christian, Straumann, Alexander, Terracciano, Luigi, Hammann, Felix, Lehmann, Frank, Beglinger, Christoph, Drewe, Juergen

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 535 KB

english, 2008

12

Data mining for potential adverse drug–drug interactions

Hammann, Felix, Drewe, Juergen

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Année:

2014

Langue:

english

Fichier:

PDF, 207 KB

english, 2014

13

Cutting Edge: The Tumor Counterattack Hypothesis Revisited: Colon Cancer Cells Do Not Induce T Cell Apoptosis Via the Fas (CD95, APO-1) Pathway

Favre-Felix, N., Fromentin, A., Hammann, A., Solary, E., Martin, F., Bonnotte, B.

Journal:

The Journal of Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 580 KB

english, 2000

14

Screening for an ivermectin slow-release formulation suitable for malaria vector control

Chaccour, Carlos, Barrio, Ángel, Royo, Ana, Urbistondo, Diego, Slater, Hannah, Hammann, Felix, Del Pozo, Jose

Journal:

Malaria Journal

Année:

2015

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2015

15

Erratum to: Green tea extract enhances parieto-frontal connectivity during working memory processing

Schmidt, André, Hammann, Felix, Wölnerhanssen, Bettina, Meyer-Gerspach, Anne Christin, Drewe, Jürgen, Beglinger, Christoph, Borgwardt, Stefan

Journal:

Psychopharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 51 KB

english, 2014

16

Development of Decision Tree Models for Substrates, Inhibitors, and Inducers of P-Glycoprotein

Hammann, Felix, Gutmann, Heike, Jecklin, Ursula, Maunz, Andreas, Helma, Christoph, Drewe, Juergen

Journal:

Current Drug Metabolism

Année:

2009

Langue:

english

Fichier:

PDF, 324 KB

english, 2009

17

Reduction of hyperbilirubinemia with hypericum extract (St. John’s Wort) in a patient with Crigler-Najjar syndrome type II

Kummer, Oliver, Hammann, Felix, Haschke, Manuel, Krähenbühl, Stephan

Journal:

British Journal of Clinical Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 399 KB

english, 2015

18

Time controlled pulsatile transdermal delivery of nicotine: A phase I feasibility trial in male smokers

Hammann, Felix, Kummer, Oliver, Guercioni, Stefania, Imanidis, Georgios, Drewe, Juergen

Journal:

Journal of Controlled Release

Année:

2016

Langue:

english

Fichier:

PDF, 940 KB

english, 2016

19

Mistaking 2C-P for 2C-B: What a Difference a Letter Makes

Stoller, Adrian, Dolder, Patrick C., Bodmer, Michael, Hammann, Felix, Rentsch, Katharina M., Exadaktylos, Aristomenis K., Liechti, Matthias E., Liakoni, Evangelia

Journal:

Journal of Analytical Toxicology

Année:

2016

Langue:

english

Fichier:

PDF, 105 KB

english, 2016

20

Pharmacokinetic interaction between taxanes and amiodarone leading to severe toxicity

Hammann, Felix, Gotta, Verena, Conen, Katrin, Medinger, Michael, Cesana, Philipp, Rochlitz, Christoph, Taegtmeyer, Anne B.

Journal:

British Journal of Clinical Pharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 309 KB

english, 2016

21

Ivermectin to reduce malaria transmission I. Pharmacokinetic and pharmacodynamic considerations regarding efficacy and safety

Chaccour, Carlos, Hammann, Felix, Rabinovich, N. Regina

Journal:

Malaria Journal

Année:

2017

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2017

22

Cytochrome P450/ABC transporter inhibition simultaneously enhances ivermectin pharmacokinetics in the mammal host and pharmacodynamics in Anopheles gambiae

Chaccour, Carlos J., Hammann, Felix, Alustiza, Marta, Castejon, Sandra, Tarimo, Brian B., Abizanda, Gloria, Irigoyen Barrio, Ángel, Martí Soler, Helena, Moncada, Rafael, Bilbao, José Ignacio, Aldaz, A

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2017

23

Identification of Any Structure-Specific Hepatotoxic Potential of Different Pyrrolizidine Alkaloids Using Random Forests and Artificial Neural Networks

Schöning, Verena, Hammann, Felix, Peinl, Mark, Drewe, Jürgen

Journal:

Toxicological Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 530 KB

english, 2017

24

Effects of a fixed herbal drug combination (Ze 185) to an experimental acute stress setting in healthy men – An explorative randomized placebo-controlled double blind study

Meier, Sibylle, Haschke, Manuel, Zahner, Catherine, Kruttschnitt, Esther, Nicolussi, Simon, Drewe, Jürgen, Liakoni, Evangelia, Hammann, Felix, Gaab, Jens

Journal:

Psychoneuroendocrinology

Année:

2017

Langue:

english

Fichier:

PDF, 63 KB

english, 2017

25

Identification of structure-specific hepatotoxic potential of different pyrrolizidine alkaloids using Random Forest and artificial Neural Network

Schöning, Verena, Hammann, Felix, Drewe, Jürgen

Journal:

Toxicology Letters

Année:

2017

Langue:

english

Fichier:

PDF, 54 KB

english, 2017

26

Effects of a fixed herbal drug combination (Ze 185) to an experimental acute stress setting in healthy men – An explorative randomized placebo-controlled double-blind study

Meier, Sibylle, Haschke, Manuel, Zahner, Catherine, Kruttschnitt, Esther, Drewe, Jürgen, Liakoni, Evangelia, Hammann, Felix, Gaab, Jens

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 944 KB

english, 2018

27

Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects

Dolder, Patrick C., Strajhar, Petra, Vizeli, Patrick, Hammann, Felix, Odermatt, Alex, Liechti, Matthias E.

Journal:

Frontiers in Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 436 KB

english, 2017

28

Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions

Leuppi-Taegtmeyer, Anne, Duthaler, Urs, Hammann, Felix, Schmid, Yasmin, Dickenmann, Michael, Amico, Patricia, Jehle, Andreas W, Kalbermatter, Stefan, Lenherr, Christoph, Meyer zu Schwabedissen, Henrie

Journal:

Nephrology Dialysis Transplantation

Année:

2018

Langue:

english

Fichier:

PDF, 540 KB

english, 2018

29

Prediction of clinically relevant drug-induced liver injury from structure using machine learning

Hammann, Felix, Schöning, Verena, Drewe, Jürgen

Journal:

Journal of Applied Toxicology

Année:

2018

Langue:

english

Fichier:

PDF, 415 KB

english, 2018

30

How far have decision tree models come for data mining in drug discovery?

Schöning, Verena, Hammann, Felix

Journal:

Expert Opinion on Drug Discovery

Année:

2018

Langue:

english

Fichier:

PDF, 813 KB

english, 2018

31

Population pharmacokinetics of oral ivermectin in venous plasma and dried blood spots in healthy volunteers

Duthaler, Urs, Suenderhauf, Claudia, Karlsson, Mats O., Hussner, Janine, Meyer zu Schwabedissen, Henriette, Krähenbühl, Stephan, Hammann, Felix

Journal:

British Journal of Clinical Pharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 469 KB

english, 2018

32

The effect of food on the pharmacokinetics of oral ivermectin

Duthaler, Urs, Leisegang, Rory, Karlsson, Mats O, Krähenbühl, Stephan, Hammann, Felix

Journal:

Journal of Antimicrobial Chemotherapy

Année:

2019

Fichier:

PDF, 187 KB

2019

33

Effects of Hypericum perforatum (St. Johnâs wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans

Scholz, Irene, Liakoni, Evangelia, Hammann, Felix, Grafinger, Katharina Elisabeth, Duthaler, Urs, Nagler, Michael, KrÃ¤henbÃ¼hl, Stephan, Haschke, Manuel

Journal:

British Journal of Clinical Pharmacology

Année:

2020

Fichier:

PDF, 1.04 MB

2020

34

Nebulized ivermectin for COVID-19 and other respiratory diseases, a proof of concept, dose-ranging study in rats

Chaccour, Carlos, Abizanda, Gloria, Irigoyen-Barrio, Ãngel, Casellas, Aina, Aldaz, Azucena, MartÃnez-GalÃ¡n, Fernando, Hammann, Felix, Gil, Ana Gloria

Journal:

Scientific Reports

Année:

2020

Fichier:

PDF, 1.30 MB

2020